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INVESTIGAÇÃO DE BACTÉRIAS GRAM-NEGATIVAS MULTIRRESISTENTES DE IMPORTÂNCIA CLÍNICA EM BIVALVES MARINHOS ISOLADOS DE MANGUE, NA CIDADE DE VITÓRIA, ESPÍRITO SANTO

dc.contributor.advisorSILVA, Quezia
dc.contributor.authorCASTRO, Lavínia
dc.date.accessioned2023-07-10T11:16:28Z
dc.date.available2023-07-10T11:16:28Z
dc.date.issued2023-12-02
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dc.identifier.urihttps://repositorio.ifes.edu.br/handle/123456789/3380
dc.description.abstractO surgimento e disseminação de bactérias resistentes a múltiplos antimicrobianos, denominadas multirresistentes, tem sido um grande problema para a sociedade, causando impactos na saúde pública e na economia. Os bivalves, filtradores marinhos, em contato com ambientes marinhos poluídos, carregam consigo a problemática das bactérias multirresistentes. O objetivo geral do estudo foi investigar bactérias Gram-negativas multirresistentes de importância clínica em sururus e ostras isolados de mangue, em Vitória/ES. Para avaliar e triar a multirresistência foi utilizada a metodologia de antibiograma com 22 antibióticos dispostos de maneira que triam ESBL e AmpC, e a resistência a antibióticos de maneira individual. De forma geral, foram encontradas ao todo 12 bactérias gram-negativas multirresistentes de importância clínica, sendo uma triagem positiva para MCR e 8 para triagem positiva para ESBL, 4 com resistência para aminoglicosídeo e 1 apresentou AmpC plasmidial. Portanto o presente trabalho alerta sobre o perigo do descaso com o meio ambiente, sendo a poluição um dos principais fatores para a pressão seletiva para o aparecimento de bactérias multirresistentes, além do aparecimento de novos casos de infecção alimentar. Palavras-chave: Enterobactérias. Bactérias não-fermentadoras. ESBL. AmpC. Ostra. Sururu.por
dc.description.abstractThe emergence and spread of bacteria resistant to multiple antimicrobials, known as multidrug-resistant bacteria, have been a major problem for society, causing impacts on public health and the economy. Bivalves, marine filter feeders, when in contact with polluted marine environments, carry the issue of multidrug-resistant bacteria. The general objective of the study is to investigate clinically important multidrug-resistant Gram-negative bacteria in clams and oysters isolated from mangroves in Vitória, ES. To evaluate and screen for multidrug resistance, the antibiogram methodology was used with 22 antibiotics arranged in a way that screened for ESBL and AmpC, as well as individual antibiotic resistance. Overall, a total of 12 clinically important multidrug-resistant Gram-negative bacteria were found, with one screening positive for MCR, 8 screening positive for ESBL, 4 showing resistance to aminoglycosides, and 1 exhibiting plasmidial AmpC. Therefore, this study alerts to the danger of neglecting the environment, with pollution being one of the main factors contributing to the selective pressure for the emergence of multidrug-resistant bacteria, in addition to the occurrence of new cases of foodborne infections. Keywords: Enterobacteria. Non-fermenting bacteria. ESBL. AmpC. Oyster. Sururu.eng
dc.format.extent36f.pt_BR
dc.languagept_BRpt_BR
dc.rightsacesso_abertopt_BR
dc.subjectEnterobactérias. Bactérias não-fermentadoras. ESBL. AmpC. Ostra. Sururu.pt_BR
dc.titleINVESTIGAÇÃO DE BACTÉRIAS GRAM-NEGATIVAS MULTIRRESISTENTES DE IMPORTÂNCIA CLÍNICA EM BIVALVES MARINHOS ISOLADOS DE MANGUE, NA CIDADE DE VITÓRIA, ESPÍRITO SANTOpt_BR
dc.typetccpt_BR
ifes.campusCampus_Vila_Velhapt_BR
ifes.author.latteshttp://lattes.cnpq.br/4317170967403796pt_BR
dc.description.affiliationIfesCampus_Vila_Velhapt_BR
ifes.advisor.latteshttp://lattes.cnpq.br/1778832016290387pt_BR
ifes.course.undergraduateBacharelado em Biomedicina
dc.contributor.memberFRANCA, Hildegardo
ifes.member.latteshttp://lattes.cnpq.br/1284874997224988pt_BR
dc.audience.educationLevel
dc.audience.educationLevel


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